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5F-MDMB-PICA is a designer drug and synthetic cannabinoid. In 2018, it was the fifth-most common synthetic cannabinoid identified in drugs seized by the Drug Enforcement Administration.
5F-MDMB-PICA is a potent agonist of both the CB1 receptor and the CB2 receptor with EC50 values of 0.45 nM and 7.4 nM, respectively
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5F-MDMB-2201 also called 5-fluoro MDMB-PICA and N-[[1-(5-fluoropentyl)-1H-indol-3-yl]carbonyl]-3-methyl-L-valine, methyl ester, 5F-MDMB-2201 is specifically an Idazole-3-Carboaminide chemical, and as such has similar chemical properties to certain chemicals used as ‘designer drugs’, such as ADB-FUBINACA and 5F-ADB.
It is a complex biochemical, and has various uses in in-vitro experimentation and as a calibration or reference sample in many forensic and mass spectrometry labs.
MMB-2201 (also known as 5F-MMB-PICA, 5F-AMB-PICA, and I-AMB) is a potent indole-3-carboxamide based synthetic cannabinoid,[1] which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends.[2] It was first reported in Russia and Belarus in January 2014, but has since been sold in a number of other countries. In the United States, MMB-2201 was identified in Drug Enforcement Administration drug seizures for the first time in 2018.
MMB-2201 is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or tert-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds
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caption id=”attachment_1150″ align=”alignnone” width=”343″]5F-Mdmb-2201 5F-MDMB-2201[/caption]
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